Proteomic Signature Library for
Staphylococcus aureus COL

summary

  • modus:
  • browse modus (regulation filter)
  • selected regulators/regulatory elements:
  • SigB-
  • threshold filter:
  • 2-fold change
  • matching:
  • 6 expression profiles
  • sorting:
  • based on function (1st) and locus (2nd)
 

expression plots

  • y-axis:
  • change of expression (binary logarithm) compared to the control at 0 min of the corresponding experiment
  • x-axis:
  • time after stress in minutes (time points of additional unstressed controls are introduced by "c")
  • experiments
  • hydrogen peroxide (abbr.: H2O2, O), diamide (abbr.: D), paraquat (abbr.: P), nitric oxide (abbr.: NO, N), fermentation (abbr.: F), nitrate respiration (abbr.: NO3 resp., A), heat (abbr.: H), puromycin (abbr.: U), mupirocin (abbr.: mupi., M)
  • color code
  • changes higher (lower) than 2x (0.5x) are colored in orange (magenta)
  • significnace:
  • asterisks (*) mark significant changes (details)
  • multiple spots:
  • multiple spots for one and the same protein are extended by a spot number (sum of all individual spots of this protein is given in parentheses)
  • protein overlap:
  • overlapping of different proteins are listed with the abbreviation (letter) of the corresponding experiment where protein overlapping have been observed
  • plot order:
  • based on function (1st) and locus (2nd)
 
  • SodA1
  • SACOL0118
  • superoxide dismutase
  • show on gel show on gel
  • detoxification (cellular processes: detoxification)
  • regulation: CodY, SigB-
  • expression plot for SodA1
  • Pyc 1 (3)
  • SACOL1123
  • pyruvate carboxylase
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • co-localization with: GyrA 2 (H2O2, diamide, paraquat, NO, fermentation, NO3 resp., heat, puromycin, mupi.)
  • regulation: CodY, SigB-
  • expression plot for Pyc 1
  • Pyc 2 (3)
  • SACOL1123
  • pyruvate carboxylase
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • regulation: CodY, SigB-
  • expression plot for Pyc 2
  • Pyc 3 (3)
  • SACOL1123
  • pyruvate carboxylase
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • regulation: CodY, SigB-
  • expression plot for Pyc 3
  • SACOL2335
  • SACOL2335
  • ABC transporter, ATP-binding protein
  • show on gel show on gel
  • transport (transport and binding proteins: unknown substrate)
  • regulation: SigB-
  • expression plot for SACOL2335
  • SACOL1985
  • SACOL1985
  • conserved hypothetical protein
  • show on gel show on gel
  • unknown function or specifity (hypothetical proteins: conserved)
  • regulation: SigB-
  • expression plot for SACOL1985
 

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