Proteomic Signature Library for
Staphylococcus aureus COL

summary

  • modus:
  • browse modus (regulation filter)
  • selected regulators/regulatory elements:
  • PurR
  • threshold filter:
  • 2-fold change
  • matching:
  • 15 expression profiles
  • sorting:
  • based on function (1st) and locus (2nd)
 

expression plots

  • y-axis:
  • change of expression (binary logarithm) compared to the control at 0 min of the corresponding experiment
  • x-axis:
  • time after stress in minutes (time points of additional unstressed controls are introduced by "c")
  • experiments
  • hydrogen peroxide (abbr.: H2O2, O), diamide (abbr.: D), paraquat (abbr.: P), nitric oxide (abbr.: NO, N), fermentation (abbr.: F), nitrate respiration (abbr.: NO3 resp., A), heat (abbr.: H), puromycin (abbr.: U), mupirocin (abbr.: mupi., M)
  • color code
  • changes higher (lower) than 2x (0.5x) are colored in orange (magenta)
  • significnace:
  • asterisks (*) mark significant changes (details)
  • multiple spots:
  • multiple spots for one and the same protein are extended by a spot number (sum of all individual spots of this protein is given in parentheses)
  • protein overlap:
  • overlapping of different proteins are listed with the abbreviation (letter) of the corresponding experiment where protein overlapping have been observed
  • plot order:
  • based on function (1st) and locus (2nd)
 
  • FolD
  • SACOL1072
  • methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
  • show on gel show on gel
  • biosynthesis of cofactors, prosthetic groups, and carriers (biosynthesis of cofactors, prosthetic groups, and carriers: folic acid)
  • regulation: PurR
  • expression plot for FolD
  • PurA
  • SACOL0018
  • adenylosuccinate synthetase
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • regulation: PurR
  • expression plot for PurA
  • PurE
  • SACOL1073
  • phosphoribosylaminoimidazole carboxylase, catalytic subunit
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • regulation: PurR
  • expression plot for PurE
  • PurK
  • SACOL1074
  • phosphoribosylaminoimidazole carboxylase, ATPase subunit
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • co-localization with: SACOL1209 (diamide)
  • regulation: PurR
  • expression plot for PurK
  • PurC
  • SACOL1075
  • phosphoribosylaminoimidazole-succinocarboxamide synthase
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • regulation: PurR
  • expression plot for PurC
  • PurQ
  • SACOL1077
  • phosphoribosylformylglycinamidine synthase I
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • regulation: PurR
  • expression plot for PurQ
  • PurF 1 (2)
  • SACOL1079
  • amidophosphoribosyltransferase
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • regulation: PurR
  • expression plot for PurF 1
  • PurF 2 (2)
  • SACOL1079
  • amidophosphoribosyltransferase
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • co-localization with: Mqo2 2 (H2O2, diamide, paraquat, fermentation)
  • regulation: PurR
  • expression plot for PurF 2
  • PurM
  • SACOL1080
  • phosphoribosylformylglycinamidine cyclo-ligase
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • regulation: PurR
  • expression plot for PurM
  • PurN
  • SACOL1081
  • phosphoribosylglycinamide formyltransferase
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • regulation: PurR
  • expression plot for PurN
  • PurH 1 (3)
  • SACOL1082
  • phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • co-localization with: Fhs 2 (H2O2)
  • regulation: PurR
  • expression plot for PurH 1
  • PurH 2 (3)
  • SACOL1082
  • phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • regulation: PurR
  • expression plot for PurH 2
  • PurH 3 (3)
  • SACOL1082
  • phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • regulation: PurR
  • expression plot for PurH 3
  • PurD
  • SACOL1083
  • phosphoribosylamine--glycine ligase
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • regulation: PurR
  • expression plot for PurD
  • PurB
  • SACOL1969
  • adenylosuccinate lyase
  • show on gel show on gel
  • nucleotide metabolism (purines, pyrimidines, nucleosides, and nucleotides: purine ribonucleotide biosynthesis)
  • co-localization with: SACOL2266 (diamide, paraquat, NO3 resp.)
  • regulation: PurR
  • expression plot for PurB
 

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