Proteomic Signature Library for
Staphylococcus aureus COL

summary

  • modus:
  • browse modus (regulation filter)
  • selected regulators/regulatory elements:
  • PerR
  • threshold filter:
  • 2-fold change
  • matching:
  • 29 expression profiles
  • sorting:
  • based on function (1st) and locus (2nd)
 

expression plots

  • y-axis:
  • change of expression (binary logarithm) compared to the control at 0 min of the corresponding experiment
  • x-axis:
  • time after stress in minutes (time points of additional unstressed controls are introduced by "c")
  • experiments
  • hydrogen peroxide (abbr.: H2O2, O), diamide (abbr.: D), paraquat (abbr.: P), nitric oxide (abbr.: NO, N), fermentation (abbr.: F), nitrate respiration (abbr.: NO3 resp., A), heat (abbr.: H), puromycin (abbr.: U), mupirocin (abbr.: mupi., M)
  • color code
  • changes higher (lower) than 2x (0.5x) are colored in orange (magenta)
  • significnace:
  • asterisks (*) mark significant changes (details)
  • multiple spots:
  • multiple spots for one and the same protein are extended by a spot number (sum of all individual spots of this protein is given in parentheses)
  • protein overlap:
  • overlapping of different proteins are listed with the abbreviation (letter) of the corresponding experiment where protein overlapping have been observed
  • plot order:
  • based on function (1st) and locus (2nd)
 
  • HemE
  • SACOL1889
  • uroporphyrinogen decarboxylase
  • show on gel show on gel
  • biosynthesis of cofactors, prosthetic groups, and carriers (biosynthesis of cofactors, prosthetic groups, and carriers: heme, porphyrin, and cobalamin)
  • regulation: PerR
  • expression plot for HemE
  • SACOL0914
  • SACOL0914
  • FeS assembly ATPase SufC
  • show on gel show on gel
  • biosynthesis of cofactors, prosthetic groups, and carriers (biosynthesis of cofactors, prosthetic groups, and carriers: other)
  • regulation: PerR, SigB+
  • expression plot for SACOL0914
  • SufD 1 (4)
  • SACOL0915
  • FeS assembly protein SufD
  • show on gel show on gel
  • biosynthesis of cofactors, prosthetic groups, and carriers (biosynthesis of cofactors, prosthetic groups, and carriers: other)
  • co-localization with: SerA 2 (H2O2), SufD 2 (H2O2, paraquat, NO, fermentation), KatA 5 (H2O2, paraquat)
  • regulation: PerR
  • expression plot for SufD 1
  • SufD 2 (4)
  • SACOL0915
  • FeS assembly protein SufD
  • show on gel show on gel
  • biosynthesis of cofactors, prosthetic groups, and carriers (biosynthesis of cofactors, prosthetic groups, and carriers: other)
  • co-localization with: SerA 2 (H2O2), SufD 1 (H2O2, paraquat, NO, fermentation), KatA 5 (H2O2, paraquat)
  • regulation: PerR
  • expression plot for SufD 2
  • SufD 3 (4)
  • SACOL0915
  • FeS assembly protein SufD
  • show on gel show on gel
  • biosynthesis of cofactors, prosthetic groups, and carriers (biosynthesis of cofactors, prosthetic groups, and carriers: other)
  • co-localization with: Hom (H2O2)
  • regulation: PerR
  • expression plot for SufD 3
  • SufD 4 (4)
  • SACOL0915
  • FeS assembly protein SufD
  • show on gel show on gel
  • biosynthesis of cofactors, prosthetic groups, and carriers (biosynthesis of cofactors, prosthetic groups, and carriers: other)
  • co-localization with: IlvA2 3 (paraquat, fermentation, NO3 resp., heat, puromycin)
  • regulation: PerR
  • expression plot for SufD 4
  • SACOL0916 1 (2)
  • SACOL0916
  • cysteine desulfurase, SufS subfamily
  • show on gel show on gel
  • biosynthesis of cofactors, prosthetic groups, and carriers (biosynthesis of cofactors, prosthetic groups, and carriers: other)
  • regulation: PerR
  • expression plot for SACOL0916 1
  • SACOL0916 2 (2)
  • SACOL0916
  • cysteine desulfurase, SufS subfamily
  • show on gel show on gel
  • biosynthesis of cofactors, prosthetic groups, and carriers (biosynthesis of cofactors, prosthetic groups, and carriers: other)
  • regulation: PerR
  • expression plot for SACOL0916 2
  • SufB 1 (2)
  • SACOL0918
  • FeS assembly protein SufB
  • show on gel show on gel
  • biosynthesis of cofactors, prosthetic groups, and carriers (biosynthesis of cofactors, prosthetic groups, and carriers: other)
  • regulation: PerR
  • expression plot for SufB 1
  • SufB 2 (2)
  • SACOL0918
  • FeS assembly protein SufB
  • show on gel show on gel
  • biosynthesis of cofactors, prosthetic groups, and carriers (biosynthesis of cofactors, prosthetic groups, and carriers: other)
  • regulation: PerR
  • expression plot for SufB 2
  • SACOL1920
  • SACOL1920
  • D-isomer specific 2-hydroxyacid dehydrogenase family protein
  • show on gel show on gel
  • central intermediary metabolism (central intermediary metabolism: other)
  • regulation: PerR
  • expression plot for SACOL1920
  • AhpF
  • SACOL0451
  • alkyl hydroperoxide reductase, subunit F
  • show on gel show on gel
  • detoxification (cellular processes: detoxification)
  • regulation: PerR
  • expression plot for AhpF
  • AhpC 1 (3)
  • SACOL0452
  • alkyl hydroperoxide reductase, C subunit
  • show on gel show on gel
  • detoxification (cellular processes: detoxification)
  • regulation: PerR
  • expression plot for AhpC 1
  • AhpC 2 (3)
  • SACOL0452
  • alkyl hydroperoxide reductase, C subunit
  • show on gel show on gel
  • detoxification (cellular processes: detoxification)
  • regulation: PerR
  • expression plot for AhpC 2
  • AhpC 3 (3)
  • SACOL0452
  • alkyl hydroperoxide reductase, C subunit
  • show on gel show on gel
  • detoxification (cellular processes: detoxification)
  • regulation: PerR
  • expression plot for AhpC 3
  • KatA 1 (5)
  • SACOL1368
  • catalase
  • show on gel show on gel
  • detoxification (cellular processes: detoxification)
  • co-localization with: SerA 1 (paraquat, NO)
  • regulation: CodY, PerR, SigB+
  • expression plot for KatA 1
  • KatA 2 (5)
  • SACOL1368
  • catalase
  • show on gel show on gel
  • detoxification (cellular processes: detoxification)
  • co-localization with: SerA 2 (paraquat, NO), Zwf 1 (paraquat)
  • regulation: CodY, PerR, SigB+
  • expression plot for KatA 2
  • KatA 3 (5)
  • SACOL1368
  • catalase
  • show on gel show on gel
  • detoxification (cellular processes: detoxification)
  • co-localization with: Zwf 2 (H2O2, paraquat), SdhA (H2O2)
  • regulation: CodY, PerR, SigB+
  • expression plot for KatA 3
  • KatA 4 (5)
  • SACOL1368
  • catalase
  • show on gel show on gel
  • detoxification (cellular processes: detoxification)
  • regulation: CodY, PerR, SigB+
  • expression plot for KatA 4
  • KatA 5 (5)
  • SACOL1368
  • catalase
  • show on gel show on gel
  • detoxification (cellular processes: detoxification)
  • co-localization with: SerA 2 (H2O2), SufD 2 (H2O2, paraquat), SufD 1 (H2O2, paraquat)
  • regulation: CodY, PerR, SigB+
  • expression plot for KatA 5
  • Bcp
  • SACOL1921
  • bacterioferritin comigratory protein
  • show on gel show on gel
  • detoxification (unknown function: general)
  • regulation: PerR
  • expression plot for Bcp
  • SACOL1541
  • SACOL1541
  • transcriptional regulator, Fur family
  • show on gel show on gel
  • regulation (transport and binding proteins: cations and iron carrying compounds)
  • regulation: PerR
  • expression plot for SACOL1541
  • SACOL1919
  • SACOL1919
  • transcriptional regulator, Fur family
  • show on gel show on gel
  • regulation (transport and binding proteins: cations and iron carrying compounds)
  • regulation: FapR, PerR
  • expression plot for SACOL1919
  • SACOL2131
  • SACOL2131
  • Dps family protein
  • show on gel show on gel
  • stress response (cellular processes: adaptations to atypical conditions)
  • regulation: PerR
  • expression plot for SACOL2131
  • SACOL1952 1 (4)
  • SACOL1952
  • ferritins family protein
  • show on gel show on gel
  • transport (transport and binding proteins: cations and iron carrying compounds)
  • regulation: Fur, PerR
  • expression plot for SACOL1952 1
  • SACOL1952 2 (4)
  • SACOL1952
  • ferritins family protein
  • show on gel show on gel
  • transport (transport and binding proteins: cations and iron carrying compounds)
  • regulation: Fur, PerR
  • expression plot for SACOL1952 2
  • SACOL1952 3 (4)
  • SACOL1952
  • ferritins family protein
  • show on gel show on gel
  • transport (transport and binding proteins: cations and iron carrying compounds)
  • regulation: Fur, PerR
  • expression plot for SACOL1952 3
  • SACOL1952 4 (4)
  • SACOL1952
  • ferritins family protein
  • show on gel show on gel
  • transport (transport and binding proteins: cations and iron carrying compounds)
  • co-localization with: GreA 1 (H2O2, diamide, NO, fermentation, NO3 resp., puromycin)
  • regulation: Fur, PerR
  • expression plot for SACOL1952 4
  • SACOL0917
  • SACOL0917
  • NifU domain protein
  • show on gel show on gel
  • unknown function or specifity (unknown function: general)
  • co-localization with: RsbW 1 (diamide, paraquat, NO, fermentation, NO3 resp., puromycin, mupi.)
  • regulation: PerR
  • expression plot for SACOL0917
 

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