Proteomic Signature Library for
Staphylococcus aureus COL

summary

  • modus:
  • browse modus (regulation filter)
  • selected regulators/regulatory elements:
  • CcpA
  • threshold filter:
  • 2-fold change
  • matching:
  • 37 expression profiles
  • sorting:
  • based on function (1st) and locus (2nd)
 

expression plots

  • y-axis:
  • change of expression (binary logarithm) compared to the control at 0 min of the corresponding experiment
  • x-axis:
  • time after stress in minutes (time points of additional unstressed controls are introduced by "c")
  • experiments
  • hydrogen peroxide (abbr.: H2O2, O), diamide (abbr.: D), paraquat (abbr.: P), nitric oxide (abbr.: NO, N), fermentation (abbr.: F), nitrate respiration (abbr.: NO3 resp., A), heat (abbr.: H), puromycin (abbr.: U), mupirocin (abbr.: mupi., M)
  • color code
  • changes higher (lower) than 2x (0.5x) are colored in orange (magenta)
  • significnace:
  • asterisks (*) mark significant changes (details)
  • multiple spots:
  • multiple spots for one and the same protein are extended by a spot number (sum of all individual spots of this protein is given in parentheses)
  • protein overlap:
  • overlapping of different proteins are listed with the abbreviation (letter) of the corresponding experiment where protein overlapping have been observed
  • plot order:
  • based on function (1st) and locus (2nd)
 
  • GluD
  • SACOL0961
  • glutamate dehydrogenase, NAD-specific
  • show on gel show on gel
  • amino acid biosynthesis (amino acid biosynthesis: glutamate family)
  • regulation: CcpA
  • expression plot for GluD
  • SACOL2161
  • SACOL2161
  • UTP-glucose-1-phosphate uridylyltransferase family protein
  • show on gel show on gel
  • cell envelope (cell envelope: biosynthesis and degradation of surface polysaccharides and lipopolysaccharides)
  • regulation: CcpA, LexA
  • expression plot for SACOL2161
  • Fhs 1 (2)
  • SACOL1782
  • formate--tetrahydrofolate ligase
  • show on gel show on gel
  • central intermediary metabolism (central intermediary metabolism: one-carbon metabolism)
  • regulation: CcpA
  • expression plot for Fhs 1
  • Fhs 2 (2)
  • SACOL1782
  • formate--tetrahydrofolate ligase
  • show on gel show on gel
  • central intermediary metabolism (central intermediary metabolism: one-carbon metabolism)
  • co-localization with: PurH 1 (H2O2)
  • regulation: CcpA
  • expression plot for Fhs 2
  • IpdC
  • SACOL0173
  • indole-3-pyruvate decarboxylase
  • show on gel show on gel
  • central intermediary metabolism (central intermediary metabolism: other)
  • co-localization with: LysS 2 (H2O2, diamide, paraquat, NO, NO3 resp., mupi.)
  • regulation: CcpA
  • expression plot for IpdC
  • GcvH 1 (2)
  • SACOL0877
  • glycine cleavage system H protein
  • show on gel show on gel
  • degradation of aminoacids (energy metabolism: amino acids and amines)
  • regulation: CcpA
  • expression plot for GcvH 1
  • GcvH 2 (2)
  • SACOL0877
  • glycine cleavage system H protein
  • show on gel show on gel
  • degradation of aminoacids (energy metabolism: amino acids and amines)
  • regulation: CcpA
  • expression plot for GcvH 2
  • GlpK
  • SACOL1320
  • glycerol kinase
  • show on gel show on gel
  • energy metabolism (energy metabolism: other)
  • co-localization with: FtsZ (H2O2)
  • regulation: CcpA
  • expression plot for GlpK
  • GlpD 1 (3)
  • SACOL1321
  • aerobic glycerol-3-phosphate dehydrogenase
  • show on gel show on gel
  • energy metabolism (energy metabolism: other)
  • regulation: CcpA
  • expression plot for GlpD 1
  • GlpD 2 (3)
  • SACOL1321
  • aerobic glycerol-3-phosphate dehydrogenase
  • show on gel show on gel
  • energy metabolism (energy metabolism: other)
  • co-localization with: SACOL0243 2 (diamide, paraquat, NO, fermentation, NO3 resp., heat, mupi.)
  • regulation: CcpA
  • expression plot for GlpD 2
  • GlpD 3 (3)
  • SACOL1321
  • aerobic glycerol-3-phosphate dehydrogenase
  • show on gel show on gel
  • energy metabolism (energy metabolism: other)
  • regulation: CcpA
  • expression plot for GlpD 3
  • SACOL1661
  • SACOL1661
  • acetyl-CoA carboxylase, biotin carboxylase, putative
  • show on gel show on gel
  • fatty acid and phospholipid metabolism (fatty acid and phospholipid metabolism: biosynthesis)
  • regulation: CcpA
  • expression plot for SACOL1661
  • PflB 1 (7)
  • SACOL0204
  • formate acetyltransferase
  • show on gel show on gel
  • fermentation (energy metabolism: anaerobic)
  • regulation: CcpA, Rex
  • expression plot for PflB 1
  • PflB 2 (7)
  • SACOL0204
  • formate acetyltransferase
  • show on gel show on gel
  • fermentation (energy metabolism: anaerobic)
  • regulation: CcpA, Rex
  • expression plot for PflB 2
  • PflB 3 (7)
  • SACOL0204
  • formate acetyltransferase
  • show on gel show on gel
  • fermentation (energy metabolism: anaerobic)
  • co-localization with: PflB 4 (NO3 resp.)
  • regulation: CcpA, Rex
  • expression plot for PflB 3
  • PflB 4 (7)
  • SACOL0204
  • formate acetyltransferase
  • show on gel show on gel
  • fermentation (energy metabolism: anaerobic)
  • co-localization with: PflB 3 (NO3 resp.)
  • regulation: CcpA, Rex
  • expression plot for PflB 4
  • PflB 5 (7)
  • SACOL0204
  • formate acetyltransferase
  • show on gel show on gel
  • fermentation (energy metabolism: anaerobic)
  • regulation: CcpA, Rex
  • expression plot for PflB 5
  • PflB 6 (7)
  • SACOL0204
  • formate acetyltransferase
  • show on gel show on gel
  • fermentation (energy metabolism: anaerobic)
  • regulation: CcpA, Rex
  • expression plot for PflB 6
  • PflB 7 (7)
  • SACOL0204
  • formate acetyltransferase
  • show on gel show on gel
  • fermentation (energy metabolism: anaerobic)
  • regulation: CcpA, Rex
  • expression plot for PflB 7
  • Pyk 1 (3)
  • SACOL1745
  • pyruvate kinase
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • co-localization with: ThrS 3 (H2O2, NO)
  • regulation: CcpA
  • expression plot for Pyk 1
  • Pyk 2 (3)
  • SACOL1745
  • pyruvate kinase
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • co-localization with: Pyk 3 (H2O2, paraquat), NrdE 2 (fermentation, NO3 resp.)
  • regulation: CcpA
  • expression plot for Pyk 2
  • Pyk 3 (3)
  • SACOL1745
  • pyruvate kinase
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • co-localization with: Pyk 2 (H2O2, paraquat)
  • regulation: CcpA
  • expression plot for Pyk 3
  • PfkA 1 (3)
  • SACOL1746
  • 6-phosphofructokinase
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • co-localization with: GapR (H2O2, diamide, paraquat, NO, fermentation, NO3 resp., heat, puromycin, mupi.)
  • regulation: CcpA
  • expression plot for PfkA 1
  • PfkA 2 (3)
  • SACOL1746
  • 6-phosphofructokinase
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • regulation: CcpA
  • expression plot for PfkA 2
  • PfkA 3 (3)
  • SACOL1746
  • 6-phosphofructokinase
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • regulation: CcpA
  • expression plot for PfkA 3
  • FbaA 1 (4)
  • SACOL2117
  • fructose-bisphosphate aldolase, class II
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • co-localization with: FbaA 3 (NO)
  • regulation: CcpA
  • expression plot for FbaA 1
  • FbaA 2 (4)
  • SACOL2117
  • fructose-bisphosphate aldolase, class II
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • co-localization with: AccA 2 (H2O2, fermentation)
  • regulation: CcpA
  • expression plot for FbaA 2
  • FbaA 3 (4)
  • SACOL2117
  • fructose-bisphosphate aldolase, class II
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • co-localization with: FbaA 1 (NO)
  • regulation: CcpA
  • expression plot for FbaA 3
  • FbaA 4 (4)
  • SACOL2117
  • fructose-bisphosphate aldolase, class II
  • show on gel show on gel
  • glycolysis/gluconeogenesis (energy metabolism: glycolysis/gluconeogenesis)
  • regulation: CcpA
  • expression plot for FbaA 4
  • SdhA
  • SACOL1159
  • succinate dehydrogenase, flavoprotein subunit
  • show on gel show on gel
  • pyruvate dehydrogenase and tca cyle (energy metabolism: tca cycle)
  • co-localization with: Zwf 2 (H2O2), KatA 3 (H2O2)
  • regulation: CcpA
  • expression plot for SdhA
  • AcnA 1 (2)
  • SACOL1385
  • aconitate hydratase
  • show on gel show on gel
  • pyruvate dehydrogenase and tca cyle (energy metabolism: tca cycle)
  • co-localization with: AcnA 2 (fermentation)
  • regulation: CcpA, Fur
  • expression plot for AcnA 1
  • AcnA 2 (2)
  • SACOL1385
  • aconitate hydratase
  • show on gel show on gel
  • pyruvate dehydrogenase and tca cyle (energy metabolism: tca cycle)
  • co-localization with: AcnA 1 (fermentation)
  • regulation: CcpA, Fur
  • expression plot for AcnA 2
  • Icd 1 (2)
  • SACOL1741
  • isocitrate dehydrogenase, NADP-dependent
  • show on gel show on gel
  • pyruvate dehydrogenase and tca cyle (energy metabolism: tca cycle)
  • regulation: CcpA
  • expression plot for Icd 1
  • Icd 2 (2)
  • SACOL1741
  • isocitrate dehydrogenase, NADP-dependent
  • show on gel show on gel
  • pyruvate dehydrogenase and tca cyle (energy metabolism: tca cycle)
  • regulation: CcpA
  • expression plot for Icd 2
  • GltA
  • SACOL1742
  • citrate synthase
  • show on gel show on gel
  • pyruvate dehydrogenase and tca cyle (energy metabolism: tca cycle)
  • co-localization with: PheS (paraquat, NO)
  • regulation: CcpA
  • expression plot for GltA
  • CcpA
  • SACOL1786
  • catabolite control protein A
  • show on gel show on gel
  • regulation (regulatory functions: dna interactions)
  • regulation: CcpA
  • expression plot for CcpA
  • SACOL0596
  • SACOL0596
  • aminotransferase, class II
  • show on gel show on gel
  • unknown function or specifity (unknown function: enzymes of unknown specificity)
  • regulation: CcpA
  • expression plot for SACOL0596
 

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