Proteomic Signature Library for
Staphylococcus aureus COL

summary

  • modus:
  • browse modus (expression filter)
  • expression template:
  • diamide (significantly induced expression) AND heat (significantly induced expression) AND puromycin (significantly induced expression)
  • threshold filter:
  • 2.5-fold change
  • matching:
  • 7 expression profiles
  • sorting:
  • based on function (1st) and locus (2nd)
 

expression plots

  • y-axis:
  • change of expression (binary logarithm) compared to the control at 0 min of the corresponding experiment
  • x-axis:
  • time after stress in minutes (time points of additional unstressed controls are introduced by "c")
  • experiments
  • hydrogen peroxide (abbr.: H2O2, O), diamide (abbr.: D), paraquat (abbr.: P), nitric oxide (abbr.: NO, N), fermentation (abbr.: F), nitrate respiration (abbr.: NO3 resp., A), heat (abbr.: H), puromycin (abbr.: U), mupirocin (abbr.: mupi., M)
  • color code
  • changes higher (lower) than 2.5x (0.4x) are colored in orange (magenta)
  • significnace:
  • asterisks (*) mark significant changes (details)
  • multiple spots:
  • multiple spots for one and the same protein are extended by a spot number (sum of all individual spots of this protein is given in parentheses)
  • protein overlap:
  • overlapping of different proteins are listed with the abbreviation (letter) of the corresponding experiment where protein overlapping have been observed
  • plot order:
  • based on function (1st) and locus (2nd)
 
  • ClpB 1 (2)
  • SACOL0979
  • ATP-dependent Clp protease, ATP-binding subunit ClpB
  • show on gel show on gel
  • protein fate (protein fate: degradation of proteins, peptides, and glycopeptides)
  • co-localization with: ValS 2 (H2O2, paraquat, NO, NO3 resp., mupi.)
  • regulation: CtsR
  • expression plot for ClpB 1
  • ClpB 2 (2)
  • SACOL0979
  • ATP-dependent Clp protease, ATP-binding subunit ClpB
  • show on gel show on gel
  • protein fate (protein fate: degradation of proteins, peptides, and glycopeptides)
  • regulation: CtsR
  • expression plot for ClpB 2
  • DnaK
  • SACOL1637
  • dnaK protein
  • show on gel show on gel
  • protein fate (protein fate: protein folding and stabilization)
  • regulation: CtsR, HrcA
  • expression plot for DnaK
  • GrpE
  • SACOL1638
  • heat shock protein GrpE
  • show on gel show on gel
  • protein fate (protein fate: protein folding and stabilization)
  • regulation: CtsR, HrcA
  • expression plot for GrpE
  • GroEL
  • SACOL2016
  • chaperonin, 60 kDa
  • show on gel show on gel
  • protein fate (protein fate: protein folding and stabilization)
  • regulation: CtsR, HrcA
  • expression plot for GroEL
  • GroES
  • SACOL2017
  • chaperonin, 10 kDa
  • show on gel show on gel
  • protein fate (protein fate: protein folding and stabilization)
  • co-localization with: SACOL2379 2 (diamide, NO, fermentation)
  • regulation: CtsR, HrcA
  • expression plot for GroES
  • CtsR 1 (2)
  • SACOL0567
  • transcriptional regulator CtsR
  • show on gel show on gel
  • regulation (regulatory functions: dna interactions)
  • regulation: CtsR
  • expression plot for CtsR 1
 

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