Proteomic Signature Library for
Staphylococcus aureus COL

summary

  • modus:
  • browse modus (expression filter)
  • expression template:
  • mupirocin (significantly induced expression)
  • threshold filter:
  • 2.5-fold change
  • matching:
  • 22 expression profiles
  • sorting:
  • based on function (1st) and locus (2nd)
 

expression plots

  • y-axis:
  • change of expression (binary logarithm) compared to the control at 0 min of the corresponding experiment
  • x-axis:
  • time after stress in minutes (time points of additional unstressed controls are introduced by "c")
  • experiments
  • hydrogen peroxide (abbr.: H2O2, O), diamide (abbr.: D), paraquat (abbr.: P), nitric oxide (abbr.: NO, N), fermentation (abbr.: F), nitrate respiration (abbr.: NO3 resp., A), heat (abbr.: H), puromycin (abbr.: U), mupirocin (abbr.: mupi., M)
  • color code
  • changes higher (lower) than 2.5x (0.4x) are colored in orange (magenta)
  • significnace:
  • asterisks (*) mark significant changes (details)
  • multiple spots:
  • multiple spots for one and the same protein are extended by a spot number (sum of all individual spots of this protein is given in parentheses)
  • protein overlap:
  • overlapping of different proteins are listed with the abbreviation (letter) of the corresponding experiment where protein overlapping have been observed
  • plot order:
  • based on function (1st) and locus (2nd)
 
  • SACOL1787 2 (3)
  • SACOL1787
  • chorismate mutase/phospho-2-dehydro-3-deoxyheptonate aldolase
  • show on gel show on gel
  • amino acid biosynthesis (amino acid biosynthesis: aromatic amino acid family)
  • expression plot for SACOL1787 2
  • IlvD 1 (3)
  • SACOL2042
  • dihydroxy-acid dehydratase
  • show on gel show on gel
  • amino acid biosynthesis (amino acid biosynthesis: pyruvate family)
  • co-localization with: IlvD 2 (fermentation, NO3 resp.)
  • regulation: CodY
  • expression plot for IlvD 1
  • IlvD 3 (3)
  • SACOL2042
  • dihydroxy-acid dehydratase
  • show on gel show on gel
  • amino acid biosynthesis (amino acid biosynthesis: pyruvate family)
  • regulation: CodY
  • expression plot for IlvD 3
  • IlvB 1 (4)
  • SACOL2043
  • acetolactate synthase, large subunit, biosynthetic type
  • show on gel show on gel
  • amino acid biosynthesis (amino acid biosynthesis: pyruvate family)
  • co-localization with: IlvB 3 (H2O2, paraquat), IlvB 2 (paraquat, fermentation, NO3 resp.)
  • regulation: CodY
  • expression plot for IlvB 1
  • IlvB 2 (4)
  • SACOL2043
  • acetolactate synthase, large subunit, biosynthetic type
  • show on gel show on gel
  • amino acid biosynthesis (amino acid biosynthesis: pyruvate family)
  • co-localization with: IlvB 1 (paraquat, fermentation, NO3 resp.), IlvB 3 (paraquat)
  • regulation: CodY
  • expression plot for IlvB 2
  • IlvB 3 (4)
  • SACOL2043
  • acetolactate synthase, large subunit, biosynthetic type
  • show on gel show on gel
  • amino acid biosynthesis (amino acid biosynthesis: pyruvate family)
  • co-localization with: IlvB 1 (H2O2, paraquat), IlvB 2 (paraquat), SACOL0431 1 (fermentation, NO3 resp.)
  • regulation: CodY
  • expression plot for IlvB 3
  • IlvC 1 (4)
  • SACOL2045
  • ketol-acid reductoisomerase
  • show on gel show on gel
  • amino acid biosynthesis (amino acid biosynthesis: pyruvate family)
  • co-localization with: IlvC 4 (H2O2, paraquat, NO, fermentation, heat, mupi.)
  • regulation: CodY
  • expression plot for IlvC 1
  • IlvC 4 (4)
  • SACOL2045
  • ketol-acid reductoisomerase
  • show on gel show on gel
  • amino acid biosynthesis (amino acid biosynthesis: pyruvate family)
  • co-localization with: IlvC 1 (H2O2, paraquat, NO, fermentation, heat, mupi.)
  • regulation: CodY
  • expression plot for IlvC 4
  • LeuD
  • SACOL2049
  • 3-isopropylmalate dehydratase, small subunit
  • show on gel show on gel
  • amino acid biosynthesis (amino acid biosynthesis: pyruvate family)
  • regulation: CodY
  • expression plot for LeuD
  • IlvA2 1 (3)
  • SACOL2050
  • threonine dehydratase
  • show on gel show on gel
  • amino acid biosynthesis (amino acid biosynthesis: pyruvate family)
  • regulation: CodY
  • expression plot for IlvA2 1
  • SACOL1562 1 (2)
  • SACOL1562
  • 2-oxoisovalerate dehydrogenase, E1 component, alpha subunit
  • show on gel show on gel
  • degradation of aminoacids (energy metabolism: amino acids and amines)
  • co-localization with: IlvC 2 (H2O2), SACOL1562 2 (fermentation, NO3 resp.)
  • expression plot for SACOL1562 1
  • ParC 2 (2)
  • SACOL1390
  • DNA topoisomerase IV, A subunit
  • show on gel show on gel
  • dna metabolism (dna metabolism: dna replication, recombination, and repair)
  • regulation: LexA
  • expression plot for ParC 2
  • SACOL2650
  • SACOL2650
  • transcriptional regulator, putative
  • show on gel show on gel
  • regulation (regulatory functions: other)
  • expression plot for SACOL2650
  • SACOL1759 1 (2)
  • SACOL1759
  • universal stress protein family
  • show on gel show on gel
  • stress response (cellular processes: adaptations to atypical conditions)
  • expression plot for SACOL1759 1
  • SACOL1759 2 (2)
  • SACOL1759
  • universal stress protein family
  • show on gel show on gel
  • stress response (cellular processes: adaptations to atypical conditions)
  • expression plot for SACOL1759 2
  • SACOL2131
  • SACOL2131
  • Dps family protein
  • show on gel show on gel
  • stress response (cellular processes: adaptations to atypical conditions)
  • regulation: PerR
  • expression plot for SACOL2131
  • IleS 2 (3)
  • SACOL1206
  • isoleucyl-tRNA synthetase
  • show on gel show on gel
  • translation (protein synthesis: trna aminoacylation)
  • regulation: T-box(Ile)
  • expression plot for IleS 2
  • IleS 3 (3)
  • SACOL1206
  • isoleucyl-tRNA synthetase
  • show on gel show on gel
  • translation (protein synthesis: trna aminoacylation)
  • regulation: T-box(Ile)
  • expression plot for IleS 3
  • SACOL2519 2 (2)
  • SACOL2519
  • conserved hypothetical protein
  • show on gel show on gel
  • unknown function or specifity (hypothetical proteins: conserved)
  • co-localization with: Ssb2 (paraquat), FolA 2 (fermentation)
  • regulation: SigB+
  • expression plot for SACOL2519 2
  • SACOL2710
  • SACOL2710
  • conserved hypothetical protein
  • show on gel show on gel
  • unknown function or specifity (hypothetical proteins: conserved)
  • expression plot for SACOL2710
  • SACOL0668
  • SACOL0668
  • hydrolase, alpha/beta hydrolase fold family
  • show on gel show on gel
  • unknown function or specifity (unknown function: enzymes of unknown specificity)
  • expression plot for SACOL0668
  • SACOL1891 1 (2)
  • SACOL1891
  • RNAIII-activating protein TRAP
  • show on gel show on gel
  • virulence (cellular processes: pathogenesis)
  • expression plot for SACOL1891 1
 

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